The Department of Biomolecular Chemistry and the Center for Human Genomics and Precision Medicine are pleased to announce that Galen Hess of Stanford University will be joining our faculty as an assistant professor in January …
News
Deleting a gene prevents Type 1 diabetes in mice by disguising insulin-producing cells
Removing a gene from the cells that produce insulin prevents mice from developing Type 1 diabetes by sparing the cells an attack from their own immune system, a new UW–Madison study shows. The cellular sleight …
A Trojan Horse? Immune cells ferry deadline fungus from mouse lung into the blood
A report today (June 27) in PLOS Pathogens shows how inhaled fungal spores exit the lung and trigger a fatal infection in mice. The study solves a mystery of mycology: Why are spores of a certain fungal strain deadly while the yeast form of that same fungus is harmless? Study leader Christina Hull, professor of biomolecular chemistry and medical microbiology and immunology at the University of Wisconsin–Madison, focuses on Cryptococcus, the most deadly inhaled fungus. The short answer, she says, is that lung macrophages abandon their posts as bodyguards and begin smuggling spores into the bloodstream.
Blockages in nerve-cell protein ‘factory’ ipmlicated in neurodegenerative disease
A molecular basis underlying the neurodegenerative condition hereditary spastic paraplegia (HSP) has been identified in a study by University of Wisconsin School of Medicine and Public Health researchers. The research, published in Cell Reports, shows how a mutation in the TFG gene – one of several linked to HSP – impairs neurons from forming the structures needed to transmit signals properly.
Butcher/Brow Labs Piecing Together the Spliceosome Puzzle One Subunit at a Time
BMC’s Heidi Dvinge featured in “New Faculty Focus”
Harrison Featured in Local Media Story on Senate Passage of 21st Century Cures Act 94-5
Assistant Professor of Biomolecular Chemistry Melissa Harrison was interviewed and her lab featured by local television station WKOW as part of its story on U.S. Senate passage of the 21st Century Cures Act 94-5. You can read the …
Krautkramer & Denu Co-Author Paper on Relationships Between Gut Microbes/Host Gene Expression in Molecular Cell
Coon, Ane Corresponding Authors of Massive New Atlas of Plant and Bacterial Proteins
Professor of Biomolecular Chemistry, Joshua Coon, and Professor of Bacteriology Jean-Michel Ane are the corresponding authors of a new article by a team of UW-Madison interdisciplinary researchers. The group’s work details more than 23,000 plant and bacterial proteins and molecular controls by which they execute beneficial relationships. The article was published in the current issue of Nature Biotechnology.
Coon Collaborates with Pagliarini/Morgridge Institute to Provide Insights to Poorly Understood Diseases
Professor of Biomolecular Chemistry, Joshua Coon, in collaboration with Morgridge Institute for Research director of metabolism Dr. Dave Pagliarini, are developing new insights into poorly understood diseases via their latest work on mitochondrial maps. Read the Morgridge …