Living systems are dynamic and complex, and their behavior may be hard to predict from the properties of individual parts. In particular, biochemical interaction networks may give rise to unexpected properties in the presence of complex interconnections and feedbacks between the genes, proteins, and metabolites involved in these networks. Computational and systems biology analyses biochemical systems (such as networks of metabolites, proteins and enzymes which comprise metabolism, signal transduction pathways and gene regulatory networks) by using genomics, proteomics, and metabolomics data together with computational and mathematical tools, in order to understand their emergent properties due to complex connections among different cellular processes.
Relevant Labs: Coon, Craciun, Fox, Harrison, Hess, Kiley, Mosher
Joshua J. Coon
Credentials: Bioanalytical chemistry, mass spectrometry and proteomics
Position title: Professor
Email:
jcoon
Gheorghe Craciun
Credentials: Mathematical and computational methods in biology
Position title: Professor (also Professor of Mathematics)
Email:
craciun
Catherine A. Fox
Credentials: Conservation and diversity in mechanisms that control the inheritance and expression of eukaryotic chromosomes
Position title: Professor
Email:
cfox
Melissa M. Harrison
Credentials: Transcriptional regulation during development
Position title: Professor
Email:
mharrison3
Gaelen Hess
Credentials: High-throughput functional genomics to investigate DNA repair and pathogenic effectors
Position title: Assistant Professor
Email:
ghess3
Tricia Kiley
Credentials: Molecular genetics and biochemistry of oxygen regulated gene expression and transcription activation
Position title: Department Chair & professor
Email:
pjkiley
Deane F. Mosher
Credentials: Extracellular matrix; cell adhesion
Position title: Professor (also Medicine)
Email:
dfm1