Anjon (Jon) Audhya
Credentials: Regulation of membrane transport during development and disease
Position title: Professor and Senior Associate Dean for Basic Research, Biotechnology, and Graduate Studies, University of Wisconsin School of Medicine and Public Health
Email: audhya@wisc.edu
Phone: (608) 262-3761; Dean's Office: (608) 263-9171
Address:
1111 Highland Avenue, 9455 WIMR 53705
The Audhya Lab Website
Education
B.S. 1997, Brown University, Providence, RI
Ph.D. 2002, University of California, San Diego (S. Emr)
Postdoctoral 2003-07, Ludwig Institute for Cancer Research (K. Oegema)
Honors & Awards
2010 March of Dimes Basil O’Connor Starter Scholar Research Award
2010 American Heart Association Scientist Development Grant Award
2010 Shaw Scientist Award, Greater Milwaukee Foundation
2012 American Cancer Society Research Scholar Award
2015 Vilas Associate Award, University of Wisconsin-Madison
2016 Vilas Faculty Early Career Investigator Award
2016 T32 Training Grant (GM008688) to Support Predoctoral Training in Molecular and Cellular Pharmacology (Renewal)
2017 H. I. Romnes Faculty Fellowship
2018 Tom Wahlig Foundation Advanced Scholarship
2018 S10 Instrumentation Grant (OD025040; An Upright Multiphoton Microscopy System to Support the Biomedical Sciences)
2020 S10 RIDE Scholar, UW-Madison Carbone Cancer Center
2021 T32 Training Grant (GM141013) to support Graduate Training in Molecular and Cellular Pharmacology
2022 Vilas Faculty Mid-Career Investigator Award
2022 Rennebohm Research Professorship
2023 American Society for Cell Biology Fellow
Research Interests
Our laboratory is committed to understanding fundamental mechanisms by which membrane proteins, lipids, and other macromolecules are transported throughout eukaryotic cells. To do so, we take advantage of numerous interdisciplinary approaches, including biochemistry, structural biology, biophysics, genetics, molecular biology and high resolution fluorescence and electron microscopy.
Additionally, we use a variety of experimental systems, ranging from animal models (rodents) to human induced pluripotent stem cells (iPSCs). We also aim to recapitulate individual steps of membrane transport in vitro, using recombinant proteins and chemically defined lipids. Our ultimate goal is to identify the regulatory pathways that control membrane deformation, which enable vesicle formation in the endosomal and secretory systems. Although basic research is the cornerstone of our program, we also seek to define pathomechanisms that underlie human disease, focusing on the impact of mutations in key trafficking components that lead to cancer, neurodegeneration, asthma, and diabetes. For more information, please visit our lab webpage: https://audhya.bmc.wisc.edu/.
Anjon (Jon) Audhya Publications
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Organizing principles underlying COPII-mediated transport
March 11, 2025 -
Multiple roles for TFG ring complexes in neuronal cargo trafficking
November 22, 2024