Anjon (Jon) Audhya

Credentials: Regulation of membrane transport during development and disease

Position title: Professor and Senior Associate Dean for Basic Research, Biotechnology, and Graduate Studies, University of Wisconsin School of Medicine and Public Health

Email: audhya@wisc.edu

Phone: (608) 262-3761; Dean's Office: (608) 263-9171

Address:
1111 Highland Avenue, 9455 WIMR 53705

The Audhya Lab Website

Education

• B.S. 1997, Brown University, Providence, RI
• Ph.D. 2002, University of California, San Diego (S. Emr)
• Postdoctoral 2003-07, Ludwig Institute for Cancer Research (K. Oegema)

Honors & Awards

• Sigma Xi Honorary Society, 1997
• Bachelor of Science, Magna cum Laude, Brown University, 1997
• Harvey Almy Baker Graduate Fellowship, Brown University, 1997
• National Cancer Institute Training Grant Award, 1998-2002
• Helen Hay Whitney Foundation Post-Doctoral Fellowship, 2004-2007
• DeLill Nasser Award for Professional Development in Genetics, 2006
• March of Dimes Basil O’Connor Starter Scholar Research Award, 2010
• American Heart Association Scientist Development Grant Award, 2010
• Shaw Scientist Award, 2010
• American Cancer Society Research Scholar Award, 2012
• Vilas Associate Award, University of Wisconsin-Madison, 2015
• Vilas Faculty Early Career Investigator Award, University of Wisconsin-Madison, 2016
• H.I. Romnes Faculty Fellowship, UW Graduate School/WARF, 2017
• Tom Wahlig Foundation Advanced Scholarship, 2018

Research Interests

Our laboratory is committed to understanding fundamental mechanisms by which membrane proteins, lipids, and other macromolecules are transported throughout eukaryotic cells. To do so, we take advantage of numerous interdisciplinary approaches, including biochemistry, structural biology, biophysics, genetics, molecular biology and high resolution fluorescence and electron microscopy.

Additionally, we use a variety of experimental systems, ranging from simple animal models (e.g. Caenorhabditis elegans) to human induced pluripotent stem cells (iPSCs). We also aim to recapitulate individual steps of membrane transport in vitro, using recombinant proteins and chemically defined lipids. Our ultimate goal is to identify the regulatory pathways that control membrane deformation, which enable vesicle formation in the endosomal and secretory systems. Although basic research is the cornerstone of our program, we also seek to define pathomechanisms that underlie human disease, focusing on the impact of mutations in key trafficking components that lead to cancer, neurodegeneration, asthma, and diabetes. For more information, please visit our lab webpage: www.audhyalab.org .

Publications

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