Anjon (Jon) Audhya

Credentials: Regulation of membrane transport during development and disease

Position title: Professor and Senior Associate Dean for Basic Research, Biotechnology, and Graduate Studies, University of Wisconsin School of Medicine and Public Health

Email: audhya@wisc.edu

Phone: (608) 262-3761; Dean's Office: (608) 263-9171

Address:
1111 Highland Avenue, 9455 WIMR 53705

The Audhya Lab Website

Education

• B.S. 1997, Brown University, Providence, RI

• Ph.D. 2002, University of California, San Diego (S. Emr)

• Postdoctoral 2003-07, Ludwig Institute for Cancer Research (K. Oegema)

Honors & Awards

2010     March of Dimes Basil O’Connor Starter Scholar Research Award

2010     American Heart Association Scientist Development Grant Award

2010     Shaw Scientist Award, Greater Milwaukee Foundation

2012     American Cancer Society Research Scholar Award

2015     Vilas Associate Award, University of Wisconsin-Madison

2016     Vilas Faculty Early Career Investigator Award

2016     T32 Training Grant (GM008688) to Support Predoctoral Training in Molecular and Cellular Pharmacology (Renewal)

2017     H. I. Romnes Faculty Fellowship

2018     Tom Wahlig Foundation Advanced Scholarship

2018     S10 Instrumentation Grant (OD025040; An Upright Multiphoton Microscopy System to Support the Biomedical Sciences)

2020     RIDE Scholar, UW-Madison Carbone Cancer Center

2021     T32 Training Grant (GM141013) to support Graduate Training in Molecular and Cellular Pharmacology

2022     Vilas Faculty Mid-Career Investigator Award

2022     Rennebohm Research Professorship

Research Interests

Our laboratory is committed to understanding fundamental mechanisms by which membrane proteins, lipids, and other macromolecules are transported throughout eukaryotic cells. To do so, we take advantage of numerous interdisciplinary approaches, including biochemistry, structural biology, biophysics, genetics, molecular biology and high resolution fluorescence and electron microscopy.

Additionally, we use a variety of experimental systems, ranging from simple animal models (e.g. Caenorhabditis elegans) to human induced pluripotent stem cells (iPSCs). We also aim to recapitulate individual steps of membrane transport in vitro, using recombinant proteins and chemically defined lipids. Our ultimate goal is to identify the regulatory pathways that control membrane deformation, which enable vesicle formation in the endosomal and secretory systems. Although basic research is the cornerstone of our program, we also seek to define pathomechanisms that underlie human disease, focusing on the impact of mutations in key trafficking components that lead to cancer, neurodegeneration, asthma, and diabetes. For more information, please visit our lab webpage: www.audhyalab.org .

Publications

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