brow lab

Welcome to the Brow lab! We are trying to understand how the chemical properties of RNA and protein have been exploited by evolution to enable complex biological processes, such as pre-mRNA splicing and transcription termination. We use the awesome power of brewer’s yeast genetics, genomics, and biochemistry to explore the workings of two biological nanomachines: the spliceosome and RNA polymerase. (Some of us also use brewer’s yeast to brew beer!) Check out our “Research” page for an overview of our studies, and the “Publications” page for our recent work. Also check out the “Lab Members” page to find out what our past members are up to now!